| # | County | State | Population | Change since 2020 | Unemployment rate |
|---|
| 1 | Val Verde County | Texas | 47,999 | 0.9 % | 5.2 % |
| 2 | Valencia County | New Mexico | 80,813 | 5.9 % | 4.5 % |
| 3 | Valley County | Idaho | 12,777 | 8.8 % | 4.5 % |
| 4 | Valley County | Montana | 7,434 | -1.9 % | 3.1 % |
| 5 | Valley County | Nebraska | 4,032 | -0.6 % | 2.6 % |
| 6 | Van Buren County | Michigan | 76,129 | 0.7 % | 5.6 % |
| 7 | Van Buren County | Arkansas | 16,152 | 2.3 % | 5.2 % |
| 8 | Van Buren County | Iowa | 7,217 | 0.2 % | 3.5 % |
| 9 | Van Buren County | Tennessee | 6,686 | 8.4 % | 3.6 % |
| 10 | Van Wert County | Ohio | 28,887 | -0.2 % | 4.3 % |
| 11 | Van Zandt County | Texas | 65,304 | 9.7 % | 4.1 % |
| 12 | Vance County | North Carolina | 42,337 | -0.6 % | 4.6 % |
| 13 | Vanderburgh County | Indiana | 180,387 | 0.1 % | 3.5 % |
| 14 | Venango County | Pennsylvania | 49,476 | -1.9 % | 4.6 % |
| 15 | Ventura County | California | 835,427 | -1.1 % | 4.8 % |
| 16 | Vermilion County | Illinois | 71,106 | -4.2 % | 5.6 % |
| 17 | Vermilion Parish | Louisiana | 57,641 | 1.1 % | 4.0 % |
| 18 | Vermillion County | Indiana | 15,516 | 0.5 % | 4.2 % |
| 19 | Vernon County | Wisconsin | 31,351 | 2.0 % | 3.1 % |
| 20 | Vernon County | Missouri | 19,787 | 0.4 % | 3.8 % |
| 21 | Vernon Parish | Louisiana | 45,819 | -6.0 % | 5.1 % |
| 22 | Victoria County | Texas | 91,949 | 0.7 % | 4.1 % |
| 23 | Vigo County | Indiana | 106,166 | 0.0 % | 3.9 % |
| 24 | Vilas County | Wisconsin | 23,948 | 3.9 % | 4.0 % |
| 25 | Vinton County | Ohio | 12,545 | -2.0 % | 5.9 % |
| 26 | Virginia Beach city | Virginia | 454,808 | -1.0 % | 3.2 % |
| 27 | Volusia County | Florida | 602,772 | 8.9 % | 4.5 % |